garageCube

Windows 10, Acer Aspire V, 16gig Ram, SSD.
Resolume Arena > Spout > Madmapper 3
Giving error when selecting Resolume // Spout input of

"Cannot create DirectX / OpenGL interop"

Have rebooted numerous times, still errors.

I suppose Spout Sender and Spout receiver won't work in your situation neither. Isn't it ?
I suppose you should run SpoutDirectX (or SpoutDXmode.exe) and select “DirectX 9”
Does it solve ?